What if you'd held PBE?
A $1,000 investment in Invesco Biotechnology & Genome ETF (PBE) at the month-end close of 2005-06 would be worth $6,939 at the close of 2026-08 — +593.9% total return, dividends reinvested. The same $1,000 in the S&P 500 would be worth $6,470.
Your scenario
Result
If you'd bought $1,000 at the start of each year
Value of $1,000 invested on January 1 of each year, held to 2026-08, dividends included.
Every year, $1,000 from 2005
| Year | Value of $1,000 | Year return |
|---|---|---|
| 2005 | $1,000 | — |
| 2006 | $1,023 | +2.3% |
| 2007 | $1,082 | +5.8% |
| 2008 | $793 | -26.7% |
| 2009 | $967 | +21.9% |
| 2010 | $1,271 | +31.4% |
| 2011 | $1,165 | -8.4% |
| 2012 | $1,327 | +13.9% |
| 2013 | $2,152 | +62.2% |
| 2014 | $2,933 | +36.3% |
| 2015 | $2,984 | +1.7% |
| 2016 | $2,301 | -22.9% |
| 2017 | $2,813 | +22.3% |
| 2018 | $2,808 | -0.2% |
| 2019 | $3,332 | +18.6% |
| 2020 | $4,187 | +25.7% |
| 2021 | $4,251 | +1.5% |
| 2022 | $3,791 | -10.8% |
| 2023 | $3,932 | +3.7% |
| 2024 | $3,974 | +1.1% |
| 2025 | $4,962 | +24.9% |
| 2026 | $5,999 | +20.9% |
Best and worst month-end to buy
The best single month-end close to have bought PBE was 2009-02 ($11.80): $1,000 then is $8,327 today. The worst was 2026-08 ($98.26): $1,000 then is $1,000.
FAQ
What would $1,000 in PBE be worth today?
A $1,000 investment in Invesco Biotechnology & Genome ETF (PBE) at the start of 2005 would be worth about $6,939 today, a total return of +593.9%. Dividends are reinvested in these figures.
What were the best and worst years for PBE?
Invesco Biotechnology & Genome ETF (PBE)'s strongest calendar year since 2005 was 2013, a +62.2% return — $1,000 held through that year became about $1,622 by year-end. Its weakest year was 2008, at -26.7%.
Does the calculator include dividends and splits?
Yes where available. Prices are adjusted for both stock splits and reinvested dividends (total return), the same measure brokerages use.
How much would $100 per month in PBE have grown?
Investing $100 at the end of every month since 2005-06 would have grown to about $83,914 on $25,500 invested.
Did PBE beat the S&P 500?
Over the same period, $1,000 in the S&P 500 index would be worth $6,470. PBE beat the S&P 500 by +7.3% in total return.
Is this investment advice?
No. Wall Street Regrets is an entertainment and education tool. Every number is a historical calculation, not a prediction, and past performance never guarantees future results.
Methodology
Invesco Biotechnology & Genome ETF (PBE) historical total-return data from 2005-06 to 2026-08, reduced to month-end closes for the tables above.
Returns use adjusted close prices from Yahoo Finance historical data — adjusted for stock splits and reinvested dividends — the same convention used by major brokerages. A "year" scenario invests $1,000 at the prior December's month-end close and values it at the latest available month-end close. Non-USD amounts are converted at historical month-end exchange rates (Yahoo Finance): to USD on the buy date and back to your currency at the latest rate, so the return reflects the currency move as well as the asset.
Month-end resolution means intra-month extremes are not captured in tables; the calculator uses exact trading-day closes where daily data is available. Figures ignore taxes, fees, and the currency effects of non-USD listings. History is not a forecast. Wall Street Regrets is entertainment, not investment advice.
What if you'd held…
Data: adjusted close prices via Yahoo Finance. As of 2026-08. Not financial advice.