What if you'd held TLSA?
A $1,000 investment in Tiziana Life Sciences Ltd (TLSA) at the month-end close of 2018-11 would be worth $681 at the close of 2026-08 — -31.9% total return, dividends reinvested. The same $1,000 in the S&P 500 would be worth $2,793.
Your scenario
Result
If you'd bought $1,000 at the start of each year
Value of $1,000 invested on January 1 of each year, held to 2026-08, dividends included.
Every year, $1,000 from 2018
| Year | Value of $1,000 | Year return |
|---|---|---|
| 2018 | $1,000 | — |
| 2019 | $724 | -27.6% |
| 2020 | $1,355 | +87.0% |
| 2021 | $644 | -52.5% |
| 2022 | $402 | -37.5% |
| 2023 | $376 | -6.7% |
| 2024 | $469 | +25.0% |
| 2025 | $999 | +112.9% |
| 2026 | $718 | -28.2% |
Best and worst month-end to buy
The best single month-end close to have bought TLSA was 2024-03 ($0.45): $1,000 then is $2,378 today. The worst was 2020-07 ($6.99): $1,000 then is $153.
FAQ
What would $1,000 in TLSA be worth today?
A $1,000 investment in Tiziana Life Sciences Ltd (TLSA) at the start of 2018 would be worth about $681 today, a total return of -31.9%. Dividends are reinvested in these figures.
What were the best and worst years for TLSA?
Tiziana Life Sciences Ltd (TLSA)'s strongest calendar year since 2018 was 2025, a +112.9% return — $1,000 held through that year became about $2,129 by year-end. Its weakest year was 2021, at -52.5%.
Does the calculator include dividends and splits?
Yes where available. Prices are adjusted for both stock splits and reinvested dividends (total return), the same measure brokerages use.
How much would $100 per month in TLSA have grown?
Investing $100 at the end of every month since 2018-11 would have grown to about $9,520 on $9,400 invested.
Did TLSA beat the S&P 500?
Over the same period, $1,000 in the S&P 500 index would be worth $2,793. TLSA trailed the S&P 500 by +75.6% in total return.
Is this investment advice?
No. Wall Street Regrets is an entertainment and education tool. Every number is a historical calculation, not a prediction, and past performance never guarantees future results.
Methodology
Tiziana Life Sciences Ltd (TLSA) historical total-return data from 2018-11 to 2026-08, reduced to month-end closes for the tables above.
Returns use adjusted close prices from Yahoo Finance historical data — adjusted for stock splits and reinvested dividends — the same convention used by major brokerages. A "year" scenario invests $1,000 at the prior December's month-end close and values it at the latest available month-end close. Non-USD amounts are converted at historical month-end exchange rates (Yahoo Finance): to USD on the buy date and back to your currency at the latest rate, so the return reflects the currency move as well as the asset.
Month-end resolution means intra-month extremes are not captured in tables; the calculator uses exact trading-day closes where daily data is available. Figures ignore taxes, fees, and the currency effects of non-USD listings. History is not a forecast. Wall Street Regrets is entertainment, not investment advice.
What if you'd held…
Data: adjusted close prices via Yahoo Finance. As of 2026-08. Not financial advice.