What if you'd held TWST?
A $1,000 investment in Twist Bioscience Corporation (TWST) at the month-end close of 2018-10 would be worth $10,171 at the close of 2026-08 — +917.1% total return, dividends reinvested. The same $1,000 in the S&P 500 would be worth $2,842.
Your scenario
Result
If you'd bought $1,000 at the start of each year
Value of $1,000 invested on January 1 of each year, held to 2026-08, dividends included.
Every year, $1,000 from 2018
| Year | Value of $1,000 | Year return |
|---|---|---|
| 2018 | $1,000 | — |
| 2019 | $909 | -9.1% |
| 2020 | $6,119 | +572.8% |
| 2021 | $3,352 | -45.2% |
| 2022 | $1,031 | -69.2% |
| 2023 | $1,596 | +54.8% |
| 2024 | $2,013 | +26.1% |
| 2025 | $1,374 | -31.7% |
| 2026 | $6,167 | +348.9% |
Best and worst month-end to buy
The best single month-end close to have bought TWST was 2023-04 ($12.48): $1,000 then is $11,409 today. The worst was 2021-01 ($165): $1,000 then is $865.
FAQ
What would $1,000 in TWST be worth today?
A $1,000 investment in Twist Bioscience Corporation (TWST) at the start of 2018 would be worth about $10,171 today, a total return of +917.1%. Dividends are reinvested in these figures.
What were the best and worst years for TWST?
Twist Bioscience Corporation (TWST)'s strongest calendar year since 2018 was 2020, a +572.8% return — $1,000 held through that year became about $6,728 by year-end. Its weakest year was 2022, at -69.2%.
Does the calculator include dividends and splits?
Yes where available. Prices are adjusted for both stock splits and reinvested dividends (total return), the same measure brokerages use.
How much would $100 per month in TWST have grown?
Investing $100 at the end of every month since 2018-10 would have grown to about $38,734 on $9,500 invested.
Did TWST beat the S&P 500?
Over the same period, $1,000 in the S&P 500 index would be worth $2,842. TWST beat the S&P 500 by +257.8% in total return.
Is this investment advice?
No. Wall Street Regrets is an entertainment and education tool. Every number is a historical calculation, not a prediction, and past performance never guarantees future results.
Methodology
Twist Bioscience Corporation (TWST) historical total-return data from 2018-10 to 2026-08, reduced to month-end closes for the tables above.
Returns use adjusted close prices from Yahoo Finance historical data — adjusted for stock splits and reinvested dividends — the same convention used by major brokerages. A "year" scenario invests $1,000 at the prior December's month-end close and values it at the latest available month-end close. Non-USD amounts are converted at historical month-end exchange rates (Yahoo Finance): to USD on the buy date and back to your currency at the latest rate, so the return reflects the currency move as well as the asset.
Month-end resolution means intra-month extremes are not captured in tables; the calculator uses exact trading-day closes where daily data is available. Figures ignore taxes, fees, and the currency effects of non-USD listings. History is not a forecast. Wall Street Regrets is entertainment, not investment advice.
What if you'd held…
Data: adjusted close prices via Yahoo Finance. As of 2026-08. Not financial advice.