What if you'd held VRTX?
A $1,000 investment in Vertex Pharmaceuticals Incorporated (VRTX) at the month-end close of 1991-07 would be worth $122,680 at the close of 2026-08 — +12168.0% total return, dividends reinvested. The same $1,000 in the S&P 500 would be worth $19,876.
Your scenario
Result
If you'd bought $1,000 at the start of each year
Value of $1,000 invested on January 1 of each year, held to 2026-08, dividends included.
Every year, $1,000 from 1991
| Year | Value of $1,000 | Year return |
|---|---|---|
| 1991 | $1,000 | — |
| 1992 | $661 | -33.9% |
| 1993 | $1,253 | +89.5% |
| 1994 | $1,016 | -18.9% |
| 1995 | $1,795 | +76.7% |
| 1996 | $2,728 | +51.9% |
| 1997 | $2,236 | -18.0% |
| 1998 | $2,016 | -9.8% |
| 1999 | $2,371 | +17.6% |
| 2000 | $9,688 | +308.6% |
| 2001 | $3,332 | -65.6% |
| 2002 | $2,148 | -35.5% |
| 2003 | $1,402 | -34.7% |
| 2004 | $1,432 | +2.1% |
| 2005 | $3,749 | +161.8% |
| 2006 | $5,070 | +35.2% |
| 2007 | $3,148 | -37.9% |
| 2008 | $4,117 | +30.8% |
| 2009 | $5,806 | +41.0% |
| 2010 | $4,747 | -18.2% |
| 2011 | $4,500 | -5.2% |
| 2012 | $5,678 | +26.2% |
| 2013 | $10,068 | +77.3% |
| 2014 | $16,098 | +59.9% |
| 2015 | $17,050 | +5.9% |
| 2016 | $9,982 | -41.5% |
| 2017 | $20,306 | +103.4% |
| 2018 | $22,454 | +10.6% |
| 2019 | $29,668 | +32.1% |
| 2020 | $32,024 | +7.9% |
| 2021 | $29,756 | -7.1% |
| 2022 | $39,130 | +31.5% |
| 2023 | $55,134 | +40.9% |
| 2024 | $54,566 | -1.0% |
| 2025 | $61,431 | +12.6% |
| 2026 | $74,805 | +21.8% |
Best and worst month-end to buy
The best single month-end close to have bought VRTX was 1992-06 ($3.75): $1,000 then is $147,216 today. The worst was 2026-08 ($552): $1,000 then is $1,000.
FAQ
What would $1,000 in VRTX be worth today?
A $1,000 investment in Vertex Pharmaceuticals Incorporated (VRTX) at the start of 1991 would be worth about $122,680 today, a total return of +12168.0%. Dividends are reinvested in these figures.
What were the best and worst years for VRTX?
Vertex Pharmaceuticals Incorporated (VRTX)'s strongest calendar year since 1991 was 2000, a +308.6% return — $1,000 held through that year became about $4,086 by year-end. Its weakest year was 2001, at -65.6%.
Does the calculator include dividends and splits?
Yes where available. Prices are adjusted for both stock splits and reinvested dividends (total return), the same measure brokerages use.
How much would $100 per month in VRTX have grown?
Investing $100 at the end of every month since 1991-07 would have grown to about $1.09M on $42,200 invested.
Did VRTX beat the S&P 500?
Over the same period, $1,000 in the S&P 500 index would be worth $19,876. VRTX beat the S&P 500 by +517.2% in total return.
Is this investment advice?
No. Wall Street Regrets is an entertainment and education tool. Every number is a historical calculation, not a prediction, and past performance never guarantees future results.
Methodology
Vertex Pharmaceuticals Incorporated (VRTX) historical total-return data from 1991-07 to 2026-08, reduced to month-end closes for the tables above.
Returns use adjusted close prices from Yahoo Finance historical data — adjusted for stock splits and reinvested dividends — the same convention used by major brokerages. A "year" scenario invests $1,000 at the prior December's month-end close and values it at the latest available month-end close. Non-USD amounts are converted at historical month-end exchange rates (Yahoo Finance): to USD on the buy date and back to your currency at the latest rate, so the return reflects the currency move as well as the asset.
Month-end resolution means intra-month extremes are not captured in tables; the calculator uses exact trading-day closes where daily data is available. Figures ignore taxes, fees, and the currency effects of non-USD listings. History is not a forecast. Wall Street Regrets is entertainment, not investment advice.
What if you'd held…
Data: adjusted close prices via Yahoo Finance. As of 2026-08. Not financial advice.